I just got my Paradigm 722 pump about 2 weeks ago,and I have had 4 different catheter sites,3 on the right side of my abdomen and 1 on my left side,the first two right side sights I had NO problems with at all but the one left side sight I had constant problems with,it would work fine until I went to give a bolus and about 1/4 to 1/2 way through the NO DELIVERY alarm would sound,and I would have to go in and try to figure what I've already given and what else needs to be given (at a dual wave bolus,WHAT FUN TO TRY AND FIGURE OUT!!) I finally got mad today and ripped out the catheter and changed sight back to right side and had no problems so far,(knock on wood!!) and as far as ripping out catheter,I know my husband tells me I have a bad temper,but I try to explain to him that it's frustrating when you want to eat but you have to sit and figure out your doses and try to figure out the problem with the pump,by the time your ready to eat your food is dried out and cold!!When I took the catheter out though it was straight(not kinked at all)and insulin was coming out of the end!!And my blood sugars stayed normal,never above 150 mg/dl.Other than this problem I love my pump,I have actually lost weight since starting the pump,I've lost 8 lbs. in 11 days. Dr. says it's because I'm no longer feeding the insulin,a common problem with diabetics trying to keep sugar levels even at certain times throughout the day.