For the past two weeks I have been having tingling in my toes and feet, sometimes one or both at the same time. I have also experienced this in my hands as well as my checks and lips. Well this morning I was ready to go to bed when both my feet began to have severe pins and needles that then traveled all the way up my calves and stopped at my knees. This went on for aprx. 15 min. It was so painful, my crying woke up my husband, who tried to rub it out, but that didn't work. I just sat in a chair and waited for it to go away; during this tingling I could not move my lower part of my legs at all, they were numb and tingling. This is not the same tingling you get when your feet fall asleep, totally different and much more painful. I have already discussed this with my neuro who said to me that it was probably a side effect from the Diamox I was prescribed for optic neuritis, but this happened before I began that medication, and I tried to tell him that, but he thinks I am mistaken. I was given a nerve cond. study on my hands that day, which showed only borderline (have no idea what that meant, but he said it was normal). Is this sort of tingling related to MS? My lumbar puncture ( I had two) showed no bands, but MRI showed several lesions in the white periventricular matter. Could this still be MS without bands?? Thanks for your time........anything to ease the tingling would be helpful, thank you. ~Jenny