I'm 40 years old female. I have been gout patient for 25 years. When I go to doctor I always hear that "o no you could not gout patient it is very early for female" but I do. I suppose it is due to hprt eynzime defficiency. But I don't know how could I stop it.
My gout attacks are indipendent from high purine diet. I'm also careful to eat low purine foods but pre mens terms my uric acid level increasing quickly.(last time it was increased from 7.6 to 9 in a two days) i'm using allopurinoles but I could not use colchisine due to the high creatinin level. For the same reason I don't have to use indometazine and colchisine together during the attacks.
I have been fighting verry strong attac for 1.5 month. It has been started from metacarpo-phalangeal joint of right hand, left foot anckle followed this then turn left foot first phalangeal foint and this morning right foot metacarp started. There is only a few days between attacks.
Although I don't have to use colchisine and indometazine I used. Then my creatinine clearens in 24 h. Urine was decreased 37. But I had to. Because I don't want t use cortisol due to side effects. I'm very desperate. Do you know any other medicine to stop the gout pain.
Gout is a consequence of increased levels of uric acid in the blood (hyperuricemia). The additional uric acid precipitates in or around the joints causing inflammation followed by great pain and, after time, deformation of the joint. Hyperuricemia is caused either by increased production of acid uric or its decreased excretion from the kidneys.
Therapy and treatment for gout has 2 phases. The first phase treats the inflammation and pain. Medications used in this phase are: Non-steroid anti-inflammatory drugs (NSAID), colhicine, and corticosteroids. Of the NSAIDs, indometacine is the most efficient. The second phase treats the hyperuricemia. This phase includes drugs that help decrease the production of uric acid (allopurinol) and other drugs that increase the excretion of uric acid through the kidneys (probenecid and anturan). The latter can be used only if the kidneys are functioning normally.
Other measures for treating gout are: decreasing the body weight, diet with less purines in the food, avoiding alcohol, coffee, physical and mental stressors, avoiding medications that decreases kidneysâ clirens and drinking more liquids (2-3 liters per day).
In your case, it seems that you can attempt to use corticosteroids and decrease body weight. You can also consult a rheumatologist for an expert opinion!
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