I get this random rash, starting on the inside sole of my feet and my palms. They look like red pin pricks under the skin, very red always extremly itchy and sometimes slightly burning. My palms get the same way but sometimes turn blistering red, hot and itchy. sometimes it goes farther and I'm completly covered in red spots that grow into welps and my eyes and lips slightly swell. It happens randomly anywhere at any time. I've even woken up with little circles of red spots on my legs that itch. I've tried benadryl, antihistamins, cortizone creams nothing really seems to help. I do have a history of anxiety and have been taking effexor for about a year but this started just a few months ago. What kind of questions can I ask my doctor so that he won't just send me away telling me to take antihistamins. I have never experienced this problem before.