Medical Questions > Mental Health > Stop Smoking Forum

This Is *not* a Just Smoke 3 More Years Post...

So i'm flipping through the channels on my tv this morning, and come across "daily planet". A show on discovery channel that documents latest inventions that will be coming out in the next few years. Not normally something I watch, but the intro was worth the wait...A vaccination for smoking. (sounds unbelievable right?)

so I sit and wait through the latest robotics, and the pillows that display text messages from your cell phone "honey i'll be late for dinner by 15 mins", and it finally comes on. (here's what I remember)

so, your respiratory system, in conjunction with your circulatory system deliver niccoteine to your brain. You inhale, it's broken down, the blood travels to the brain carrying niccoteine, making you "feel better" when you smoke and "feel like cr*p" when you don't. Now the brain works mysteriously...

There's a "flap" of sorts at your brainstem that blocks harmful or unnecessary items in your blood from being delivered to the brain, antibodies, and immunizations being two of them...Niccoteine *not* being one of them.

So this company in sweden has come up with an ingenious idea. They have created a vaccination that "tricks" your immune system into thinking that niccoteine is an **invader**! So what happens?

You smoke, the niccoteine is broken down, goes into your blood stream and is immediately attacked by your immune system. The antibodies attach themselves to the niccoteine particles, and are blocked at that "flap" into your brain stem.

So you're smoking, but your brain is saying you're not, and can pretty much smoke yourself silly and get no satisfaction from it...Hence, no need to smoke anymore.

These guys are in 3rd phase (i believe) of testing, and so far have a 60%!!! Success rate after 2 or 3 doses...With minimal side effects. For those who don't think too highly of 60% here's the stats...

Cold turkey - 5%
patch - 33%
psychotherapy - 30%
smokeless gum or cigs - 25%

they are hoping to have it released by 2010, and have heightened their success rate, and drop the side effects completely.

Now as I said, this isn't a post to say "smoke for 3 more years, then get cured"...I just wanted to share this information and allow others to potentially look into it themselves, or make up their own minds about what to think about it.
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replied May 23rd, 2006
Experienced User
Yea, it does sound unbelievable, although I believe science does a lot of good, i'm highly suspect of anything new....................Will this vaccine make just nicotine undesirable or will it also make other sustances ie food, drink etc undesirable. Will they be some sort of allergic reaction?An immune response? We as humans naturally look for the easy way out......The magic pill, the patch, the latest fad, a guru, the vaccine etc that'll be the final answer to rid ourselves of this addiction.............When the real answer(in my opinion) is the hard way.............As it is with most addictions...........Willpower!

I know easier said then done, however I don't want to find out 10 years down the road this stuff causes birth defects, mutations or even cancer.

Even my overweight daughter wants the easy way out........"ma, isn't there some pill I can take to lose weight?" or "when i'm older can I get liposuction?"
what happened to good old fashioned eating well and exercise........Yikes!..........Sounds like an effort, man.

Don't get me wrong, i'm not totally dismissing it.....And who knows?!
But to me, at least, it'll be a true victory.................When you can say.......
I did it myself!!!!! :)
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replied May 23rd, 2006
I agree totally, and unfortunately I don't have many answers to the questions you posed at the begining of your reply, I only really put down what I could remember. Like I stated though, I just posted this for the information value, and am allowing others to make their own mind up about what to take from it.


I do believe that everything that happens to your body can be controlled mentally, you hear all the time about people beating cancer cause they refuse to fall victim to it. But there are some people out there who don't have that strength of will.


For all anyone knows this shot could be loaded with saline, and the belief that it will make them stop smoking itself could wind up solving the problem. Who knows?


Personally, I want to quit by my own will, and would rather not have to wait, or have to say "i couldn't do it on my own".
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replied February 25th, 2007
Experienced User
I have read about this drug also. From what I gather, it is basically a chemically induced cold turkey. Which basically means that the person will have no choice, but to go through withdrawal, because the nicotine is not reaching the brain.

To be clear though. Withdrawal is not that bad. It is the fear of not being able to stop those craves by the only way we know how. By smoking a cigarette that makes it bad.

The pharmecudical companies, the Sugeon General, the majority of quit smoking experts, and the media have pounded into our heads that quitting smoking is one of the hardest things we will ever do. We even have our own past failed attempts to prove this. This has built up a wall of fear of quitting and makes the person quitting feel that only a lucky few get to quit.

The truth is anyone can quit, when they learn how and quitting is not scary when you come to understand nicotine addiction.

The physical part of addiction actually plays the smallest part in quitting. It is the brainwashing and association triggers that plays the largest part and is the biggest obstacle for the person quitting.

I don't know of any NRT or miracle drug that can change how a smokers perceives cigarettes.

I do know that education of this addiction will help immensly.

The problem with this miracle cure is this. I think I read to where ithe process lasts a year. You take periodic shots in this time. This keeps nicotine from reaching the reward pathways. What it doesn't do though is change how that person sees cigarettes. They may very well go through this whole process feeling as if they are depriving themselves of smoking. This is the usual downfall to anyone's quit.

A person who has quit for a long time and then smokes a cigarette, does not do it for the need for nicotine. They do it, because they are still under the illusion that a cigarette will do something for them. This is the downfall, because once the person re introduces nicotine back into their system, the cycle of addiction starts over again. This makes a person believe that they are physically addicted forever and makes quitting seem daunting.

I have suffered a lot from this nicotine trap. I have tried to quit smoking countless times. It wasn't until I learned about nicotine addiction that quitting became fairly easy. I never had willpower. I never had a quit last more than 3 weeks. I was never stronger than my addiction. The trick for me was that I got smarter than my addcition.

Happilly, I haven't smoked a cigarette in over 2 years and 7 months and I know that I am done smoking.

Education is key. It will erase the fear people quitting have.


Eric

P.S.

Those stats on quitting are a little inaccurate. Go to the American Cancer Society and the 2003 report shows that 91% of the people who successfully quit , do it cold turkey.

Australia did a similar study in 2006 and 88% in australia quit cold turkey.

The NRT study success rate has a lot of fine print that they don't want any of us to know about and a lot of the stats given are from the pharmecudical industry and not independent research that is in no way affiliated with them.

Remember within 72 hours most nicotine is gone and this is where withdrawal peaks. Within 2 weeks all physical withdrawal is usually over.

The biggest obstacles are association triggers and the brainwashing caused by addiction.
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