I also sneeze after injecting a large dose of cocaine, its weird cause you get nauseous, then right when you feel like your gonna throw up a sneeze comes out most people I know just throw up but we sneeze. Why? I couldn�t find anything online about this happening . But I have a theory � hammer412 you where on the right track most sneezes are caused from irritation in your nose mainly from allergies but some people sneeze from sunlight, this is a condition that affects 18-35% of humans called ACHOO syndrome, most people with this are photo-sensitive and have a allergic reaction to bright light. I don�t know about you but I don�t sneeze from bright light at all. So I don�t have ACHOO right? But after some research I found out what causes the disorder. Overstimulation of the trigeminal nerve is responsible for all sneezes people with ACHOO syndrome have an association between this nerve and the optic nerve. So finally cocaine use cause�s you pupils to dialate, which in turn fires off the trigeminal nerve and you sneeze. Ithink this happens because when injecting it reaches the brain so fast the liver cant filter it and the chemicals that protect your body from foreign/harmful substances don''t have time to work and an overstimulation of your optic nerve occurs. So maybe we have ACHOO and just aren�t that photo-sensitive and light doesn�t stimulate are optic nerve as much as the injecting cocaine does . But I�s guessing anyone with ACHOO would sneeze from cocaine use, mainly injecting cause it stimulates your optic nerve so much.