Ibuprofen overdose affects the liver primarily. I would also NEVER suggest mixing medications: once you choose a pain killer, stick to your choice. Mixing medications could promote an autoimmune reaction, especially when you start to mix ibuprofin, acetominophen, and methylmorphine within a 24 hour period. Even though I highly disagree with pain relievers because of the negative effects on the liver and kidney, I would recommend taking NO MORE than the recommended dosage of your painkiller of choice, then placing a very warm, damp towel on the affected ear until the towel cools, then having your son lay in such a manner that the affected ear is facing downwards but not resting directly on a pillow, to allow for drainage and hopefully relief of pressure. If the pain is really unbearable, ask a doctor to prescribe a stronger pain killer. Above all, stop the ibuprofen overdose IMMEDIATELY or there very probably will be serious and unpleasant side effects. 200-400 mg ever 4-6 hours.