I am also sick with mono and have an enlarged spleen. You really should be on bed rest. Don't lift anything that feels to heavy. Don't participate in any sports or rough housing. An impact could cause the spleen to rupture. I always feel more pressure after eating too much, so try and eat small portions but more often during the day. Try to stay in bed as much as possible and if your better half thinks your faking, let them know they have a good chance of already having it and soon it will be them needing you! In sickness and in health right! You can't get better if you don't rest! And if you are a smoker you have to quit for now.

I had mono when I was 10 years old. I have had the sharp pain under my ribs on the left side since 2004. I will be 50 years old in Jan. I have suffered through removal of kidney stones twice, extreme female problems and colon problems. I have had MRIs, Cat Scans, Dozens of X-Rays and hundreds of blood test and 5 different doctors. My regular doctor ran a test for mono and lime disease and I was positive for mono disease. I have ran a fever for years and had to resign from my job due to the pain I was going through. I have had hives as large as silver dollars and after years, I am still fighting hives. I take a tremendous amount of medication since this sickness effects my diabetes, cholesterol, eyesight, joint pain and everything else. THis is very depressing since I have been fighting this for so many years. I would not wish this on my worst enemy.

I am learning that mono isn't being taken as seriously as it should be. I had it myself this past march. The doctor didn't know I had it. She just put me on some random antibiotic to get rid of the swollen lymph nodes and I ended up with a full body rash. Turns out that will happen if you take antibiotics when you have mono. Since then, I have almost constant fatigue. I was working out everyday anyway. But I was catching every little thing that came around. I have a fever, sore throat and fatigue almost weekly. And I am tired no matter how much I sleep. So i went back to the doctor who told me that mono takes a full five years to escape your system, and reprimanded me for exercising. She told me quite specifically NOT to exercise for the next YEAR. She said to quit softball and be a couch potato unless i want to end up relapsed and in the hospital. The words "couch potato" are REALLY not good as I am also ADHD. I understand the fatigue. Sometimes it's infuriating, because my mind is racing but my body is exhausted. The husband should absolutely be supportive. Exhaustion like this cannot be faked. And the test results don't lie. As far as your spleen, maybe go see and endocrinologist. Someone who specializes in glands. That knows how to REALLY look at things. You definitely don't want to rupture your spleen. And rest as much as you can. I know it's not always feasible. I'm a massage therapist. My job is very VERY physical and taxing. But I rest as much as I can. There is nothing else TO do. Just listen to your body.