Acne has a complicated and still unsolved etiology (reason for manifestation). There are four factors that have a major impact on acne development. The first is SEBORRHOEA. Seborrhoea is the increased production of tallow by the suet glands in the skin. Seborrhea is genetically conditioned but its clinical expression depends on various influences like hormonal function (testosterone), psycho-emotional health, neuron-vegetative status, nutritive health… Seoncdly, MALE SEX HORMONES (androgens) stimulate the suet glands. The development and production of the suet glands depends upon androgens. Due to testosterone levels, males are more frequently and badly affected by acne than females. The third factor for acne development is FOLICULAR HYPERCERATISIS. The outgoing canals of the suet glands open into skin follicles from where skin hairs originate. Epidermal cells in the skin follicles over-proliferate and create a tap that prevents the suet from going out. Finally, BACTERIA (especially Propionibacterium Acnes) digest the stagnated suet provoking inflammation.
As you’ve read, acne can’t be explained only by testosterone impact. Acne doesn’t have its own cycle but it usually recedes after the age of 20.