What symptoms did you have leading your physician to order the screen? Were you having symptoms or are/were more active lesions showing up?

I have recently started using therapy. There is only one lab that actually performs this test. Did your physician do a baseline or just decide that since you were not (i assume) improving that ordering a $900 test which would show the presence of these antibodies proves a correlation.

I don't know either, but switching to another interferon is a crapshot. If your neurologist is really concerned about this issue he/she should switch you to another class of drugs that do not run the risk of neutralizing antibodies....Jeez---i had to make like eight calls to find out about this test, convince both the insurance company and my physician they should perform a baseline test....And then, what is the rational behind all this?

No disrespect intended, but docs---give us an informed opinion on this stuff and some good studies on this issue please---otherwise ms patients will spend $$$ needlessly.

I would be interested to hear other peoples experiences on this topic too.
I have recently changed from Rebif to Avonex for convenience sake because I couldn't receive Rebif easily where I am living and I was sick of injecting 3 times a week. But, after 4 odd months I am thinking about switching back to rebif because of various flareups I've been encountering.. but I think it is probably still too early to tell. From what I have been reading Rebif is slightly stronger and superior to Avonex. If I continue to have symptoms I will switch back without a doubt I am not sure this is a gamble I want to take for too much longer. I spent 8 odd years on Rebif and I hated it but at least but body was in relatively good form considering. Now I'm dealing with all sorts of old symptoms and reminders of the way things were going before I started Rebif in the first place.
Anyway as I said before it is probably still to early to tell.
Fingers crossed.