Hey, I just wanted to post the information I have for you. I'm about to start on lutera right now, but I have been on aviane for 5 or 6 months. The only reason it's changing is because I just moved, and my new pharmacy carries lutera, not aviane, but they are both the generic for for allese. I have had no problems with aviane so far, and i'm guessing that will stay the same for lutera since they're both the generic for the same rx. Anyways, I too was on depo, as my first for of birth control about 1 1/2 years ago. I had horrible side effects. And I mean bad. Sex actually became painful, to be exact, every time my boyfriend inserted, no matter how lubricated I was, I felt like someone was slicing my insides with a knife. Sorry to be so graphic, but I have heard of some other people having bad effects like this too, and I thought maybe if you had the same bad effects, that you might be more like me with lutera. Also on depo, I had my period for 6 months straight, no breaks, and as i'm sure you can guess, that sort of slowed down the sex life a little, as did the pain I was experiencing. After speaking to my gyno. I switched to the pill form, I don't remember exactly which one anymore. The pain I felt during sex shortly dissapeared after I switched, probably completely went away in about a month, and my period went back to normal, but I soon found myself having extremely painful cramps during my period, bringing me to tears almost. It was strange for me, I never had cramps at all before this pill. I also felt myself becoming depressed, I had no sex drive left at all, and I became extremely moody all the time. I basically wasa upset with something no matter what. After talking to my gyno. Again, she switched me to aviane. She said it was a low-dose formula for pills, like ortho-tri-cyclin. Soon after switching to this pill, I felt the side effects slowly go away. I only switched 3 months ago, and still have a few side effects from before, like being moody, but even that I can feel getting much better. I am slowly gaining back my libido too, luckily. And you have to remember that the old horomones can take up to a year to fully leave your system. So i'm hopeful that after remaining on aviane, lutera and the likes, that I will eventually go back to the girl my boyfriend fell in love with, and not the mean, moody witch I became after becoming sexually active and going through all those bad side effects. I'm sorry I wrote so much, but hopefully it will help you a little to know there is someone else out there, who has also had bad side effects with depo, and loves aviane and those generics. Good luck!