SLE is an autoimmune disease wherein the immune system attacks a host's internal structures by producing antibodies against them. These antibodies bind to different structures (antigens), creating immune complexes. These complexes precipitate in the small blood vessels where the blood is filtrating (capillaries) throughout the (kidneys, skin, joints, muscles, heard, brain…). Then, the immune complexes in these organs provoke inflammation. The kidneys are the most commonly affected organs; SLE’s prognosis depends upon the progression of kidney failure. SLE is treated with immunosuppressive medicines to decrease antibody production. SLE is unpredictable. SLE mainfests both exacerbations (worsening condition) and remissios (relief) that may last for years.