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Conditions and Diseases > High Blood Pressure and Hypertension Forum > Diagnosis and Treatment of Primary and Secondary Hypertensio
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Q: Diagnosis and Treatment of Primary and Secondary Hypertensio
asked by: DoctorQuestion on January 14th, 2006
My father lives in Hong Kong and has hypertension for a few years. He did not have any treatment since he followed a very strict but balanced diet and exercises regularly hoping that this would help. However, his blood pressure seems to spike at night recently, especially as soon as he lays down. He saw many doctors (even cardiologist & neurologist). At first he thought his gallbladder stones was the cause so he had it removed but after that, and despites all the different medications these doctors prescribed, none of them works. The neurologist even prescribed 3 MAOIs to him (which almost landed him in the ER once again.) We all puzzled, including the doctors in Hong Kong, of what might have caused the blood pressure to rise at night. His blood work, stress test & EKG test all came out normal. My father is very desperate for any suggestion, especially for any recommendation in medication since he is very concern about his life right now. Thanks.


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Dr. Nikola Gjuzelov , MD
replied on January 23rd, 2006
High Blood Pressure, Hypertension, High Cholesterol Answer A
I can’t tell you anything about proper therapy for your father because I need more information about the level and type of his hypertension (HTA). However, I can first tell you that HTA has more unknown than known causes. Roughly more than 95% of all cases cannot be etiologically traced (Primary, idiopathic, essential hypertension). Various genetics, metabolic rates, nutritive elements, life-style, and psychic state (as well as other factors) are most likely the root of its pathogenesis. In less than 5% of all cases of HTA, then, clinicians are able to identify its cause: suprarenal tumors or vascular disorders of the kidneys (Secondary, symptomatic, non-essential hypertension). Primary HTA is an incurable life-lasting disease... BUT IT CAN BE CONTROLLED by using a combination of pharmaceutical medications and a prescribed diet (less salt). Its treatment is life-lasting, too. Putting the blood pressure at normal levels is very important to prevent atherosclerosis which causes heart attacks, hypertensive heart disease, cerebral insults, renal-vascular disorders, hypertensive retinopathy… Sometimes the HTA is very resistant to any therapy (malignant hypertension) and the complications mentioned above occur very quickly. Treatment and prognosis of Secondary HTA depends upon a number of conditions. In your father’s case, several biochemical blood analyses must first be completed to identify the type of HTA (Primary or Secondary). He also can examine the prescence and varying levels of the following: cholesterol (LDL and HDL), triglycerides, glucose, urea, creatinin, ions(Na , K ), aldosterone, adrenaline. An ultrasound of the kidneys and suprarenal glands is also recommended.


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