Your opthalmologist must have made a mistake since blephamide is a medication the contains both anti-biotic and corticosteroid. If herpes simples keratitis is really what your sister has, it is a viral infection and should be best treated with 1% viroptic (trifluridine - topical antiviral). Topical corticosteroid treatment is used depending on how deep the kerititis has affected your sister's cornea. Also, since she is exterience pain around here orbit, does she any have other symptoms such as skin blisters? If she does, the diagnosis has to be differentiated from herpes zoster ophthalmicus. The dendrite kerititis seen in herpes simplex and herpes zoster are different, therefore make sure your doctor had made the right diagnosis, or maybe choose another doctor that can differentiate between an anti-biotic and an anti-viral medication.