I started taking seasonale for the second time just about 5 weeks ago due to painful periods. The first time around(age 21), I had no issues with the pill, no breakthrough bleeding, or any side effects. If you would have asked me about the pill I would have swore by it. However, this time around (age 25), I have had breakthrough bleeding for about 7 days now (not consistent, but still annoying), around the same time the breakthrough bleeding started I started developing a rash on my arm, that has since spread to my other arm, knee and behind my ear, I can't focus, and today I felt very disoriented and weak while playing basketball, which is very uncommon considering I am always playing. I have recently lost weight, but that was not due to the pills, rather a change in life style, and my diet has not been altered very much either. So I would recommend the pill to people, but I would caution them that it is really luck of the draw, you will either love it or hate it.