Loss of Muscle With Weight Loss

I'm at a complete loss of where to go next. My spouse has lost about thirty plus pounds over a period of four months without dieting. She has tmj but I manage to feed her high protein meals that have no weight gaining attributes. She has been to a number of physicians; a couple offered lyposuction while others said she looked good. Part of the problem is I can't locate a dr. Who can advise what treatment is advisable. She is also epileptic and now experiences acute depression and talks about the problems she has non-stop.
Granted she looks great but this type of weight loss has me extremely concerned to include the muscle hanging loose. She excercises regulary but to no avail...........Any ideas ? We've also had treatment on the tmj at the uw in seattle....No luck.