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Q: Methotrexate And Fatigue
asked by: stephcoyne on September 7th, 2005
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Help! Looking for ways to combat extreme fatigue! I suffer from ra and take 20mg methotrexate weekly and just can't function day of dose and day after. And the rest of the week still feel exhausted in general. Don't know where to turn - no-one seems to understand that a 'good nights sleep' isn't making a difference. Does anyone have any ideas that will help me get my life back. Wondering what's worse - joint pain or fatigue from meds?!

Take care, steph
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khott
replied on October 24th, 2005
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I take methotrexate (20mg/week) along with plaquenil and just recently started humira. My ra doc and primary doc have me on 1cc of vitamin b12 each week and I am feeling better. I give myself the shot which is the same size as an insulin needle.
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EmoHealth
replied on October 25th, 2005
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Sleeping problems used to plaque me. I found that my problems were getting worse because of a condition that most doctors don't test for, leaky gut syndrome.


I have an awesome meal planner sheet that gets you back on track and gives you an energy boost.
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1seudo
replied on March 7th, 2008
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Need to know
I have been taking methotrexate for 3 months and am starting to experience severe depression. I have post traumatic stress disorder and cannot tell if this is just an abnormally serious flare up or if it's being triggered by the medication. I am desperate to know if anyone else is experiencing these same side effects.

Thanks!
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laceysmom
replied on May 21st, 2008
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methotrexate
I also take 20mg. of methotrexate weekly, and am very fatigued the day I get the needle, I am not too bad the day after, but I am tired all the time, my ra Dr. is having having blood work done to see if my b12 is low. I know how you feel I could sleep 24\7, although I have to work part time so I do have to get up and get moving when I have to work. I also have fibromialga, I am not sure which is more painful, I think the fibro. may win. Take care and hang in there!!!
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