The immunosupression can cause plenty of problems not limited to gettign contagious disease easier, cancer, and digestive trouble. Advice: wash your hands religiously. Try not to touch your eyes very often. Avoid people at work etc that have a cold or something else. I have noticed hand tremors and sleeplessness as the main problems I have run into with my txp meds. That and god-forsaken prednisone causing bone loss. I have been diagnosed with osteopenia and have to slam the calcium constantly and exersize a ton to increase my bones density. Take care of your kidney and it will take care of you.