Yall do know there are different types/severities of acne right?
Acne vularis (types) and the preferred treatments (Copyied from Wikipedia Article)
Comedonal (non-inflammatory) acne: local treatment with azelaic acid, salicylic acid, topical retinoids, benzoyl peroxide.
Mild papulo-pustular (inflammatory) acne: benzoyl peroxide or topical retinoids, topical antibiotics (such as erythromycin).
Moderate inflammatory acne: benzoyl peroxide or topical retinoids combined with oral antibiotics (tetracyclines). Isotretinoin is an option.
Severe inflammatory acne, nodular acne, acne resistant to the above treatments: isotretinoin also known as Accutane, can be prescribed by a doctor, or contraceptive pills with cyproterone for females with virilization or drospirenone.
I was diagnosed with nodular acne. I was prescribed Accutane by my dermatologist, and took it for 8 weeks. I have not had an 'outbreak' since.
All in all, the medication is expensive, and it does require a dermatologist to prescribe, so you're going to have to get your finances and coverage in order if you are looking to treat nodular acne.
Also, fellas. DON'T attempt to take contraceptive pills for women as a treatment for your acne, as female hormones can literally KILL YOU!
EDIT: Forgot to mention, I took Accutane 8 years ago, so I have not had an outbreak for the past 8 years.