I do not believe there is a set time frame as to how long she will suffer. I do not understand why she will not allow them to close the hole in her spinal column.
It is rather painless when they patch it and she will be given almost immedeate relief.
In the mean time she needs to be kept well hydrated with a good sport style drink. (gatorade, powerade...) this will allow for her csf to continue to properly regenerate as it is lost.
If she refuses to go get this fixed, you should just go somewhere else while she suffers alone for a while. I know it sounds mean but when you get back, she will probably be ready to go get it fixed.
There is no reason for her to suffer with such a simple procedure.