Hi there wondering if anyone can help,for the last few years I have been sufering from a variety of distressing symptoms which sometimes can wax and wane.I had tia attack 4 years ago in brainstem region and eventually they diagnosed hole in heart which they said was probable cause.However I have had numerous strange symptoms since then including dizziness,sometimes ver brief acute vertigo,inbalance,pins and needles in upper limbs which can be there for few months then vanish,headaches ,visual disturbances which only last for about a second,stiffish neck which feels burning sometimes,muscle and joint pain an fatigue to name a few as well as a few mysterious attacks of angioedema.I have had numerous tests done which include 3 mri scans(1 was an mri/mra and another was done with contrast dye)1 ct scan and I ct angiography done to look at blood vessels in brain,3 lumbar punctures and numerous blood tests performed.All the scans were completely normal except for 1tiny high signal region in the left centrum semi ovale which was present in all scans and unchanged on them all.All blood work normal including ana,compilment andantibodies to extractible nuclear antigensnegative,liver and kidney function normal,hiv negative.The only abnormal test is my lumbar puncture which has shown a mild but very slightly increasing pleocytosis(6wbc,17wbc,26wbc over 3 years but csf protein is normal as well as all other csf indicators)can anyone help,thanks paolo.