I had tried every ssri there is, really..... And to add I gained 50 pounds in the process. After wanting to literally jump off a mountain, my doctor put me on lithium. I thought it was a "god send ". I was a little sluggish for about three weeks and thought it was going to be like all the other meds, but around week four things begin to happen. I felt like I did when I was approximately 16 years old! I had a desire to live. I had energy, I even left my home and begin interacting with people. Thats really the person that I am. Depression and/or mental illness is so dibilitating. But anyway it worked for about six months, now I am falling again. Meaning, I have no desire, nor the energy to get out of bed, my hygeine is slipping and I hate to hear the phone ring and to interact with people. I have called doctor. Praying that what was once working will work again. Oh! By the way some people gain wait on lithium....I lost 43 pounds.

As of right now I am taking wellbutrin, risperdal, and zoloft. They just recently put me on zoloft about 2 1/2 months ago. At first, the medication change made me very tired in the morning and almost not functionable at school until about 10:00. But that only lasted about 3 weeks. I am fine now and I feel okay. Some days I just want to die and I want to go off on people for no reason at all. Other days I am extremely sociable and just want to keep talking and talking. I feel good about everything and everything in my life is good some days and then others I hate my life and everything makes me angry. So I don't know...Most of the time my medicine keeps me stable. I am right in between. Not extremely happy or sad, just right. So, I think the first few weeks on a new medicine may make you seem different and you'll notice it, but after that things should even out.