Depression Forum - Tried a Couple Antideprnts. Then Zoloft-can It Work Already

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Q: Tried a Couple Antideprnts. Then Zoloft-can It Work Already

asked by: j2010 on April 15th, 2005

New User

I was on lexapro for 3 months. Didn't seem to help with the depression but helped my anxiety. Made very so tired and drowsy that I couldn't continue to take it. I then tried effexor xr for close to 6 weeks -75mg- and it didn't seem to work at all. Made my anxiety worse. Then the Dr. Put me on zoloft at 50mg. I took it the first time today. About and hour after, I felt very sedated but much more calm. Then, about 4 hours later, I started to feel great. It is weird. Could zoloft work this fast, after just one dose? I am asking this because I went directly from one med to the other. Anyone experience this? Thanks.

Replies(5)

jazzman

replied on April 18th, 2005

New User

Effexor is a multiple reuptake inhibitor. At 75mg it would act like an ssri, so if you made a direct switch to zoloft then the mechanism by which seritonin is inhibited may still have been in action. It is really difficult to tell. Some people find zoloft stimulating which in helps their mood, as side effects are usually immediate effects. Just give the zoloft a chance and see how you are in a month.

A question though... Effexor is usually used only after ssris have failed, as it affects other nuerotransmitters once you up the dose. So why did your doc not just up the effexor?

j2010

replied on April 18th, 2005

New User

Thx jazzman. We talked about upping the effexor to 150mg but the effexor had been making me extremely anxious. To the point of no return it felt. When I was on lexapro, it took care of the anxiety but not the depression. So, he thought we should just back off of the effexor and try zoloft. He said he thought this was my next best option.

It really seems to be working after 4 days though. I just didn't think I would notice a change so quickly. Definitely tell for sure in a month. Thanks again.

janice70

replied on September 17th, 2007

New User

Zoloft

I WAS ON PAXIL FOR SEVERAL YEARS. I HAD TO MAKE A CHANGE CAUSE MY BODY BECAME IMMUNE TO IT, BASICALLY I EXHAUSTED IT TO ITS FULLEST. ANYWAY, I WAS THEN PUT ON EFFEXOR, WHAT A NIGHTMARE!!!!!! I HAVE JUST BEEN SWITCHED TO ZOLOFT AND I SWEAR ONLY BEING ON IT FOR ABOUT 4 DAYS I FEEL SOOOOO MUCH BETTER. I THOGHT IT WOULD TAKE AT LEAST 2-3 WEEKS TO FEEL ANY CHANGE. IS THIS ALL IN MY HEAD,WISHFUL THINKING? I HOPE NOT. IS THERE ANYONE ELSE THAT HAS HAD THIS SAME EXPERIENCE? PLEASE LET ME KNOW.

quinnsboy7

replied on October 2nd, 2007

New User

Zoloft

HI i am on zoloft and have been for about 6 months now. I started on 50 then went to 100 and i am now on 200. Zoloft is a very good pill but it is not for everyone as it does have some strong side affects when you first start them. A friend of mine tried them but was put onto something else as it made her worse. So i guess you could say it is horses for courses. Each thing works diffrently for other people if it works keep with it if not move on.

FoodDRadio

replied on October 2nd, 2007

Experienced User

is it just me or does someone else think this is just the same person advertising their product?

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