As hotasfrick mentioned, it's not totally secure. The reason is, there are other medications and health store supplements available to counteract the effects of injectable depo. Male and female fitness experts, bodybuilders, athletes, and supermodels are all aware of these as they benefit from these hormones to slim their body, gain muscle, and gain energy, all the while taking extra supplements to counteract the possibility of affecting sex drive, testosterone production (for men), and impotence. Simple supplements such as tribulus, tongat ali, hcg, or zinc are used for men. And if men use another female drug clomophene citrate (clomid) and taximophen citrate (nolvadex) used for inducing ovulation in women, and protecting against female sexual problems... The man's testosterone level will actually increase, and very effectively allow the use of depo.
So... Depo on it's own, will make a man sterile over around 3 months of injections. (typically how long is take for perminant sterility to set in). But with the use of other supplements it can be counteracted.
The more I browse this forum, the more I realize I know a lot of weird stuff... :/
j