I'm 29 yrs old and I have rheumatoid arthritis, which has left me crippled to the point that I am very limited in the activities I can do, including driving and work. As a result I became very depressed and had high anxiety. At first I tried Wellbutrin with no success, then my doctor put me on Cymbalta, b/c it was supposed to be the this fantastic new wonder drug. My doctor slowly stepped up my dosage to 120 mg, and one month later I STARTED HAVING SEIZURES. I have no history of epilepsy, nor does my family. Yet my first seizure occurred almost exactly one month after I started 120 mg of Cymbalta. I have 3 more grand mal seizures since and numerous mild seizures. Cymbalta also put me in a terrible "brain fog," where I would zone out all the time, and sometimes I felt almost like I was floating outside of my body. I would talk jibberish to my husband, although in my head I thought I was talking clearly. Then my insurance wouldn't fill it the way my doctor had written it, so I went 2 days without. I thought I was having a meltdown! I cried uncontrollably all day long. When my husband asked what was wrong, I couldn't answer him. But now let me answer how it actually helped as far as my depression went: AWFUL. It made me even more depressed than I was before, but I thought, given my medical condition, that I was asking too much to expect a wonder pill to make me feel better. So I stuck with it. I couldn't sleep most nights, usually slept until 2:00 in the afternoon, would shower, and then go back to bed. I prayed to sleep my life away. I stopped going out, stopped talking to my family and friends, just cut myself off from everyone. I even tried to leave my husband b/c I told him he deserved better then me. So after all of these seizures, I figure it may be the Cymbalta causing it and ask my doctor to take me off of it. He agrees and puts me on Prozac. And I feel a gazillion times better!!!!! I feel like I have my life back!!!!

You couldn't pay me to ever try Cymbalta again!!!! I've talked to quite a few doctors. Half of them love it, half of them think it's junk! Of course everyone's situation is different, but here's my experience.