I had brain cancer and took chemotheraphy both intravenously and orally. I also had 30 very intense radiation treatments directly to my brain. When I was 42, I had gone through menopause. Could the chemotheraphy and/or the radiation have caused or contributed in any way to this? I am 45 now and feel like I am starting to have more hot flashes, night sweats, and moods swings again. My husband said he heard on the radio that some report showed a link between chemo and premature menopause, and that since it was premature, the symptoms were spread out over a longer period of time (would tend to come and go). I was wondering if there was anything to this report.