Are you doing research on this topic? I'm certainly not one to rule out what you say, and agree with you that it would be interesting from a scientific standpoint to find out about this.

I've asked you this before, and you've not responded, but i'm curious -- what is your affiliation? The reason I ask what your affiliation is is because you may have connections to resources that the rest of us don't. If you truly are in a medical field, and what you say is true, you should be able to find many sources of funding for a clinical study on this issue. I haven't seen studies like this anywhere in the literature.

Most of the literature i've seen says that anxiety, depression, anger, etc., leads to an increase in crp. Increased crp levels over time can lead to serious heart problems and other problems. All of these studies, however, were done on a mixture of patients with and without anxiety because the tact of the studies were to determine the effect of stress factors on otherwise healthy individuals. Nowhere, however, were diagnosed anxiety sufferers solely tested for crp level.

In order for this to be a successful study, I think there needs to be three groups tested for crp: anxiety sufferers with chest pain and heart symptoms, anxiety sufferers without these symptoms, and non-anxiety sufferers.

There it is -- now all we need is someone to do the research!

Crp doesn't lead to heart problems because it is a just marker of cardiovascular disease. Actually, more of a vascular disease marker
than heart disease (which may be secondary to the vascular problems).
A marker is not a physical cause that can lead to subsequent dysfunctions
but rather a measurement that something from a physical point of view is
not right.

Nobody can state that anxiety (again, somebody has to come and quantify
it before talking about it) leads to increased crp levels. For this you need
proof that the anxiety symptoms have to be present for a while long
before the crp levels are increased.
That means, to pretend that anxiety leads to increased crp levels you
need to find a significant number of anxiety patients with normal crp
levels.

The significance of crp has already been studied in the large a
academic centers, but that doesn't mean that they are published.
Just look at the resistance to any post that tries to make the endothelium
dysfunction and its complications known to the general public.

I agree with the clasification of the groups of study populations that you
suggest. And the patients may need to start doing their own research if
they want to stop chasing their tails with the all in your mind anxiety
talks.
And they should understand that looking for help towards doctors that
say that their brain is dysfunctional is not helpful. The reason is because
the medicine is incomplete as a profession and it is fraudulent as a
science because is trying to cover up everything that cannot be fixed by it.

It definitely wouldn't hurt to check this out! This person could be onto something! We all know that stress and anxiety does effect the cardio, the high protein could have something to do with this.
Sincerely,
sandy

those are some pretty strong statements. I think that's the sort of thing that is getting people upset, rather than the possibility of endothelial dysfunction playing a role in these symptoms. Many individuals are able to overcome their symptoms through current medical means, including both psychological and phsychiatric. Certainly, western medicine has its pitfalls, but I think to call it "fraudulent" is a bit extreme. Let's not throw the baby out with the bathwater here!

In spite of your strong tone against the mental health profession, I do think that you are correctly warning us not to rely solely on psychiatry and psychology to address our problems. Treatment for anxiety needs to be a part of a bigger picture, treating mind, body, and spirit. But until modern medicine -- the only system we have right now -- can confirm these statements, we're stuck with what we have right now, which is research primarily based on brain chemistry and behavioral patterns. Thankfully, these work in treating the symptoms for many individuals.

My only concern with chasing every new "discovery" in relation to anxiety is the unhealthy response that many anxiety sufferers have in this regard. Many people become extremely fearful that they have life-threatening diseases, and that generates even further worry. Knowledge may be power, but if that knowledge isn't helpful, then what good is it? To sit here thinking about all the terrible diseases I might have prevents me from living a happy and fulfilling life.

What do you know of that can bolster endothelial function? I have read that certain enzymes and amino acids (such as l-arginine) encourage healthy vascular response. Anything else you'd like to share here? I'm also curious who is researching this, even if it isn't published. What are your sources?

Another point that comes to mind, getting back to the crp indicator, is what is the cause of death of most anxiety sufferers. Again, a study such as this has not been performed as far as I know. If a majority of people with anxiety, who treat it and live symptomless for years, end up having heart problems and stroke, then that's something that we really should know! If we answer that question, we can target these problems.

The endothelial function can be preserved for all your life as long as you
do not have arterial and heart congenital problems.
You did mention some things to bolster the endothelial function, but the
most important thing is to prevent the deterioration of it due to a
defective vascular growth factor gene.
The only real thing so far is to engage in a genetic treatment clinical trial
as early in your life as possible (best before 10 yrs, which is usually long
before you get any symptoms like "anxiety" and others) to try correcting the congenital vascular abnormalities before endothelial dysfunction advances.

Therefore, as long as there is no widespread vascular and heart testing
in the children, and I do not mean only in the wealthiest countries
such as usa, uk and others, there will always be medical tragedies
later on.

The thing with psychiatry is that it uses biased and superficial public
labelings (eg. Mentally disabled, etc) on people that are suffering much
more than mentally. It virtually breaks the empathy of the more fortunate
towards the less fortunate (eg. People committed into psychiatric yards)
by and with the secrecy and power of this profession.
You can say whatever you want, but hiding the suffering does not
diminish it!
This is why I am pleading for a merge of the psychiatry into the
palliative care where the human dignity is still being preserved.

Of course, in order to preserve the status of psychiatry, there are
people whose problems are ignored although they might still get a
chance if everything would have more transparency and treated in
time. Until then, these people (or the people from the poorer countries
in the future) will be medical casualties.

Forgot to say it. If you are an anxiety sufferer and you have kids,
you should probably do some research on which medical centers offer
gene therapy clinical trials in cardiology.
if you find any, go there and test your children for possible heart
problems. It's better to be safe than sorry.