I have never reacted that way to cipro (goodness knows I was given it in college everytime my urine showed protein...Ugh!).
I did, however, react to some sulfa drugs that way...Rashes, achy joints...Etc. Of course, they did not know I had lupus then. I have since found out that sulfa based items are not always good things for some lupus patients.
I would call my doctor, jenn. It sounds like you need something else...Or to make sure the sinus infection's stress on your body has not caused you to start flaring!
Hugs and feel better,
ladybrannon