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Q: Lupus Related Hives??
asked by: WrldTraveler on July 27th, 2004
New User
Hi, I am new to this site, and just started doing some online research to try and find some answers... Doctors can't seem to help, and i'm becoming really frustrated. For the past four months, I have had hives and random swellings (sometimes a lip, sometimes an eye lid, sometimes a finger). In the beginning, I had them only every 3rd or 4th day, with little regularity. For the past 5 weeks, however, I have had quite severe hives **every** single day, with little variation in intensity. They are pencil eraser to quarter sized, sometimes merging into big groups, covering my legs from the tops of my feet to my hips, the lower part of my torso, and my arms. The one place on my body that has remained relatively clear is my chest and upper back. They are unmercifully itchy, and antihistimines (i've been taking the new claritin hives relief) aren't working nearly as well these days they used to. I have been to a gp, who didn't even let me finish with my bizarre symptoms before he started writing a prescription. I then moved on to an allergist, thinking that it had to be an allergy issue. She did the scratch-test for 49 foods and also cats, and all came back negative. She also did a blood test and found that I had elevated levels of ana. She reccomended that I stop taking a sulfa-based antibiotic, bactrim (i had been taking off and on for 3 years for acne), which I did. After these original tests, my symptoms became increasing worse, and I went back 6 weeks later for further testing. She had little to suggest, since I had changed shampoo, soap, etc., so she did another blood test, this time including celiac sprue in the mix. It came back negative, but I still had elevated levels of ana. She recommended that I see a rheumatologist, which puzzled me. The only link I have found on the internet between rheumys and hives is lupus, so i'm hoping that someone here can tell me i'm not crazy!! Laughing my mom has lupus (a very mild case) and she also has celiac sprue. I don't know if this makes a difference, but any info that may help...
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LadyBrannon
replied on July 27th, 2004
Active User, very eHealthy
Hi there! Smile

i have had serious skin reactions with my lupus. Keep in mind though that there are several autoimmunes that mimic lupus, it may not be lupus.

I would keep a detailed diary and make an appointment to see the rheumy! Keep track of all the tests they do and their results.

Wishing you the best...And some answers!
Ladybrannon
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el725
replied on August 19th, 2004
New User
Lupus Related Hives
Hi all,
i was out in the sun yesterday for just a little while--took the usual precautions. This morning I woke up with hives on all of my joints--back of the knees, elbows, around my hip joints. I called my rhuemy & he told me to try a couple of things including benadryl and as a last result if they didn't work, I could go on the prednisone. I'm sure benadryl will help with the itching, but I can only take that if I just give in to staying in bed all day--it totally knocks me out. I already take allegra-d daily, so another antihistamine probably wouldn't help. My question is--has anyone found anything for extended relief short of the benadryl or prednisone?
Lizbet
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gabrielleadams
replied on April 25th, 2009
New User
Lupus and hives
For me Benadryl is of no use in that regard, except in that if I take it infrequently, it puts me to sleep and thus out of my misery (that effect wears off after a few days of taking it). None of the prescription allergy meds have any effect whatsoever. I've tried them all.

Prednisone is truly a med of last resort, because it eventually causes your bone tissue to die, among other horrible side effects. You may end up having to take a short course of it if your hives are severe, but try to avoid letting them put you on it on an ongoing basis unless you're sure they have tried every other treatment available. Doesn't hurt to seek another opinion.

Best bet is to keep a symptom diary. You may not test "positive" for an actual allergy in the classical sense, but many triggers may either be something they don't test for, or the reaction at the time of testing may be too slight to be counted as a positive result; especially in the case of lupus, since reactions to allergens tend to come and go. For me (I do have lupus), sunlight is a big trigger, and some medications make me break out, others simply make me itch like mad without any hives. Avoiding your triggers is definitely the way to go. Finding out what those are can be tricky. Log your activities, foods, any exposures that are suspect. Wish there were an easier remedy. Good luck.
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