Multiple sclerosis should not have any
impact on knee replacement surgery in a
technical matter of speaking. The real
problem is, what the benefit from knee
replacement would be if the patient is
already disabled because of the multiple
sclerosis. If the patient's legs are
immobilized because of the multiple
sclerosis there won't be any benefit from
the knee replacement. But if the multiple
sclerosis is under control and hasn't
caused leg paralyzes yet, knee replacement
is worth to be done if knee condition
requires that.