Do you have any other information raju ? Like how old is your wife ? Is she taking any medications like hormone treatments ? Is there anything she eats that makes her itchy ? Is she allergic to anything like soaps, detergents, washing powder? Maybe you could ask the doctor to do some allergy tests ? It sounds like she is eating or using something that she is allergic to. You need to really take notice of when she has a bad case of itchiness, and have a look at what she has just eaten or been in contact with. There are hundreds of different allergies, some people are allergic to condoms and lubricants, cleaning products, some plants that give off pollen, chemicals, medicines, cosmetics, and one common one is soap and washing powder. Does she have any other medical problems ? Maybe if you include all this info in your next post we can help you a bit more.
Good luck!! Suzy...