Prostate Cancer Forum - radiation after negative bone scan ?

Cancer > Prostate Cancer Forum > radiation after negative bone scan ?

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Q: radiation after negative bone scan ?

asked by: mdyar on February 16th, 2008

New User

this question is by proxy for my father who had a R.P. 24 months ago.

a radio-oncologist solicited a saturday call recently and said "to come on in & we'll zap it into oblivion".[ start feb .25 th]

wise or unwise?

some internet postings on salvage radio-therapy are bleak on their scientific efficacy e.g. 75 % chance of elevated p.s.a. within 5 years ,overall.

others a much more positive prognosis.[ depends on many variables]

too much info. to correlate for an amatuer.

dad's original diagnosis was gleason 3 4, [7] psa =10, dre =negative,

pathologist upgraded diag. to t3c [ s. vessicules involvement]
note : cancer grew independently at site.
no nodes.

psa 6 weeks after R.P. = .03 , 3 months thereafter = .03, .05, .05,.09, .083, .115.[latest]
recent bone scan was negative.

Replies(3)

MandMs

replied on February 19th, 2008

Extremely eHealthy

Is your father experiencing rising PSA and cancer recurrence that affects seminal vesicles?

mdyar

replied on February 19th, 2008

New User

yes , psa appears to be on the rise though at very low levels still.
should be at nadir or nil.

as far as cancer recurrence , being locally in the prostatic bed or systemic [ distant]at this point ,know one know's or can know.

but i appears there is definitely a bio-chemical failure.

i was suspicious of the good doctor's solicitous phonecall , but i recently had some help on another forum, saying by his personal experience with P.C., that time is of the essence in this scenerio.
he ran the statistics[ dads #'s] thru a flow chart , and came up with a 50 percent chance for salvage radio-therapy to work.

heads or tales !

MandMs

replied on March 13th, 2008

Extremely eHealthy

What are his last PSA readings?
Radical prostatectomy, usually, includes complete removal of both seminal vesicles.
If there are retained portions of the seminal vesicle, retained seminal vesicle tissue may secrete PSA (meticulous removal of the entire seminal vesicle should be routine with radical prostatectomy) PSA levels should be undetectable after radical prostatectomy. So, for patients whose PSA levels fail to become undetectable after radical prostatectomy, it may be appropriate to consider imaging before initiating adjuvant therapy such as radiation.

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