Most infections with high-risk HPV types do not lead to cancer because the immune system is able to remove the virus before it causes problems. When it does occur, cancer takes time to develop. It usually takes 5 years to 10 years, or even more, for cancer to develop.
Infection with "high risk" types of HPV may lead to cancer of the cervix, vulva, vagina, anus, or penis.
Penile cancer is extremely rare, especially in circumcised men and affects about 1 in every 100,000 men.
Anal cancer is very rare cancer, too, especially in men with healthy immune systems and people with HIV infections are more likely to develop it.
Some experts are trying to learn whether Pap smears of the anus might help protect men from developing anal cancer.