Allergies toward contraceptives such as the Nuva Ring or antihistamines such as Benedryl are very rare but still possible. You're not required to take those two medicines and can postpone using them, but you could be allergic to substances other than those two. You can perform an allergic skin-based test(s) to identify the substances that you are, in fact, allergic to. Sometimes allergies can be due to infective diseases like Hepatitis B, for example. Therefore, in addition to the skin test(s) you can request standard blood analyses (blood count, sedimentation rate, liver status, kidney status, hemoglobinâ¦) plus IgE-antibodies levels. You can consult a dermatologist about your condition in order to begin the process.