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side effects of methyldopa while pregnant (Page 2)

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December 29th, 2010
METHYLDOPA
I was 8 weeks pregnant and doctor diagnosed me with hbp, prescription was methyldopa. i took 2 tablets, 1 at night and 1 during the day and when i went to my prenatal, my fetus was not viable. mind you, i had gone to prenatal 2 weeks prior with a viable fetus. 1 will never know why my fetus actually died, but i believe in my heart the meds had a great impact.

holistic health, mother providers and doctors who will listen and care about your concerns are the best remedies to caring for you and your unborn's health

god bless you all!
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replied February 18th, 2011
To everyone who has lost their fetus, I'm truly sorry to have read your stories. However, I'm currently a medical student who came across this thread as I was studying this drug, and would like to provide this side of the fence.

Physicians are not healers, we only practice giving medicine. The best cure is not a treatment, but prevention. Thus, the holistic approach of eating right, exercise, and so forth is certainly the best way to lower blood pressure. When a drug is prescribed, it is usually for two reasons: 1)the physician is in the belief that the benefits outweigh the possible side effects, OR 2)the patients are pressuring them to do so (I've had classmates who are guilty of this).

Methyldopa is a false neurotransmitter that acts on receptors in the CNS and blocks them to decrease total peripheral resistance. In English, it works on your nerves to lower your blood pressure. Your doctor has probably prescribed this to you because there are not many drugs that have been shown to have no side effects in pregnancy. For example, labetalol, which someone mentioned, reduces heart rate and and contractility, which doesn't even sound good for the fetus, whose HR is typically upwards of 150 beats per minute. A quick search of the internet on studies of methyldopa seems to reveal that animal studies of methyldopa on pregnancy has no effect. A human control study has yet to be done, but just as someone said, who would be willing to subject their fetus to a "study"? A surveillance study however seems to reveal no association between the drug and congenital defects.

From a clinical standpoint, doctors are looking after the mother first and foremost, simply because without the mother, the fetus cannot survive. Thus, if you have hypertension, the physician is prescribing this to you because your health and well-being comes first (this is BY NO MEANS saying they don't care about the well-being of the fetus). In most cases, they consider the benefits of controlling your high blood pressure greater than the risk of methyldopa to the fetus, which currently shows no association. Again, this is probably of no consolation to those who lost their unborn child, but the side effects nausea, vomitting, and headaches rarely, if ever, cause a miscarriage. Please talk to your physician and ask them to provide you with their full analysis of why they are prescribing any drug for you and ask them to weigh the risk and benefits for you before you stop taking the medication on your own. They have gone to school and continue to stay educated on these topics for many years, they should be considered experts in their line of work.
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replied March 15th, 2011
I totally agreed with you romanwahoo; somehow I have the bad side effect of this meds methydopa.... I was taken HTN meds over the years, after my first pregnancy due to P.I.H / toxemia; while taking my prescribe metropolol xl 25mg + triamterene/HCTZ 37.5/12.5mg & so far my BP was controlled sbp < 125,while on this meds. I got pregnant, & now I am 6-7 weeks of course my PCP change my meds. to methydopa 250mg which i start last friday 3/11/11, & as a matter of 2 days taken this meds twice a day, I became swollen severely swollen all over & more my face, that my BP-140/90 & my headache was bad I feel so heavy, My PCP ordered to stop the meds & monitor BP 2x/day so far my sbp < 125. I am also very anxious b'coz my 1st prenantal check up will be on friday & knowing now that i am still swollen alittle bit esp. my lower extremeties & my face. although my main concern is my health & also the baby,I am afraid of the rebound effect of cutting/off the HTN meds. suddenly over the years. but somehow since i know my self & now i more eating fruits & avoiding salty food, and also being on a healthcare profession my knowledge is giving me some awareness...I am hoping that the baby will fine & holding on well.... & that will make me at peace..... every medication has different A.S.E/ drug interaction to each individuals, it's just happen were among of them or I am among of them. I will keep the updates & post my latest status.
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replied May 3rd, 2011
I am 50 years old and was prescribed Methyldopa for high BP in 1987 while pregnant with my second son. The only side effect I had at the time was sleepyness. I needed a nap every day!!
After my son was born healthy, my BP lowered to safe levels, and I discontinued the drug.
Eight years later I became pregnant with my daughter. I was living a healthier lifestyle and did not develop high BP during this pregnancy.

My concern is... My son.. who is now 23 years has always been a very "Calm" child. He didn't cry much as an infant.. he has always been my cuddler. As he grows older I am worrying that he is too "calm". He seems depressed and has no drive to improve his situation. I am wondering if Methyldopa during the development of his nervous system has permanently shut off some of the nerve connections that would make him more animated, active and less depressed. My son has normal to above normal intelligence and normal BP for a 23 year old.
I'd be interested in a medical professional's thoughts on this please!
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replied March 23rd, 2012
i have high blood pressure and iam 16 weeks pregnant and i take the methyldopa 500 mg twice a day since i knew i was pregnant the doctor says we wont give any medicine unless its safe , and i had no side effects and i haven't throw up once until now i sleep more and go to the bathroom more but i think that is because pregnancy
but sure sometimes i feel that any medicine could affect the baby but the high blood pressure could also affect the baby and cause miscarriage
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replied May 12th, 2012
missed schedule taken of meds
I am on my daily doses of methyldopa. what should i do if i miss the said schedule intake of the certain time. I was about to take it last night at 12 midnight but i took it at 3 am for a every six hours schedule that is suppose to be at the time set of 6-12-6.. what shloud i do if i did miss the dose that i was suppose to take? should i resume to the original schedule?
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replied May 30th, 2012
Ohh my God. Am trying to concieve and don't even know if i already am. Was put on methyldopa as i hav hbp. After reading this, i don't know ht to do. is there a more safer drug?
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replied June 18th, 2012
methyldopa
I am on methyldopa. I have been for about 3 weeks now. At certain times of the day I feel very tired, dizzy and agitated so I just go to bed until it wears off. Im 36 weeks pregnant so I've got the expected tiredness aswell. If I didn't take this medication I could be alot worse off. I have a heart condition and any more extra pressure on my heart could seriously harm me and my baby. I say although it makes me feel a bit sick and tired that's nothing to what could happen if I didn't.
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replied January 24th, 2013
Hi ladies i have suffered hbp since i was 21 they found it in my 3rd pregnancy very late and i delivered at 28 weeks, baby fine healthy adult now, i am now 43 and have been blessed again what a shock at my age but im 4months and things are going well so far, i was put on methyol dopa and have had side effects of being tearful very easily, tired,a little nausea, and a terible taste in my mouth from 4 weeks preggy..now it can be the pills or it can be just simply related to being pregnant, my baby is fine i am under a high risk team who keep a well managed eye on me and my baby, what i do recommend is DO NOT STOP TAKING THE MEDS IF THEY ARE MAKING YOU FEEL THAT BAD SEE YOUR DR AND GET THEM CHANGED, belive me high blood pressure and no meds is more dangerous to you and your baby than a medication than makes you feel not so great...my baby is doing fine so far so good, i had an experience 23 years ago that i will never forget i nearly lost my life and that of my baby, also i have been on other bp meds for years and am sure they contributed to miscarriges, as soon as i found out i was preggy this time my dr stoped my usual meds straight away put me on methyoldopa and 4 months later we are still going strong and with my faith in the lord we will get there.
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replied June 11th, 2013
Question
I know this post is a little out of date but I am looking for advice. I have HBP that ranges from - 130/90 to 165/110. While I must admit I have been very stressed over the past year, I tried everything possible to lower the blood pressure without medication. Dietry changes, walking 30minutes daily I am 28 and my BMI is perfect for my height.I have no other health issues and my blood pressure has been diagnosed as hereditary. However, when I went to the doctor he prescribed Olmesartan 10mg tablet one each day. I know this is a low dose. After traking this dose for 14days my BP lowered to 90/60 and I was feeling faint in work. I probably shouldn't have, but I started taking half of the tablet each day and my BP is now perfect. 120/80 or less! I want to become pregnant and know that I will have to change medication. However 125-500mg per day as described above seems a very high dose. I would like to know if this standard dose through out pregnancy or does this depend on many factors?! I hope someone can advise. Thank you.
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replied June 11th, 2013
Question
I know this post is a little out of date but I am looking for advice. I have HBP that ranges from - 130/90 to 165/110. While I must admit I have been very stressed over the past year, I tried everything possible to lower the blood pressure without medication. Dietry changes, walking 30minutes daily I am 28 and my BMI is perfect for my height.I have no other health issues and my blood pressure has been diagnosed as hereditary. However, when I went to the doctor he prescribed Olmesartan 10mg tablet one each day. I know this is a low dose. After traking this dose for 14days my BP lowered to 90/60 and I was feeling faint in work. I probably shouldn't have, but I started taking half of the tablet each day and my BP is now perfect. 120/80 or less! I want to become pregnant and know that I will have to change medication. However 125-500mg per day as described above seems a very high dose. I would like to know if this standard dose through out pregnancy or does this depend on many factors?! I hope someone can advise. Thank you.
|
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replied June 11th, 2013
Question
I know this post is a little out of date but I am looking for advice. I have HBP that ranges from - 130/90 to 165/110. While I must admit I have been very stressed over the past year, I tried everything possible to lower the blood pressure without medication. Dietry changes, walking 30minutes daily I am 28 and my BMI is perfect for my height.I have no other health issues and my blood pressure has been diagnosed as hereditary. However, when I went to the doctor he prescribed Olmesartan 10mg tablet one each day. I know this is a low dose. After traking this dose for 14days my BP lowered to 90/60 and I was feeling faint in work. I probably shouldn't have, but I started taking half of the tablet each day and my BP is now perfect. 120/80 or less! I want to become pregnant and know that I will have to change medication. However 125-500mg per day as described above seems a very high dose. I would like to know if this standard dose through out pregnancy or does this depend on many factors?! I hope someone can advise. Thank you.
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