I have very strong suspicions that there are very few actual depression cases base on brain chemistry alone. I really wonder about my own. I very much believe that I just have real reasons to be depressed.
My son in-lay and daughter pillaged my house, and trashed it around Thanksgiving. She left with my grand daughter, and my new born grand son, before I ever got to see him.
I worked 46, 12hr nights in a row. The last one I worked 20hrs. I came home exhausted, and dirty to my home. There was nothing left but trash. It was 4 days before Christmas. I was scrambling like a mad man to catch up on my bills. My mail was lost. I still, today, need to catch up on a couple of them.
I found my self sitting in a trash out house, alone , on Christmas Eve. I left messages with my church to find a place. I never got a call back. I went to sleep late. I woke up at 12:40 am. I couldn't sleep. There wasn't anything open at that hour, I just knew I had to get out. I need gas. I found one station that had just opened. I gave the young man a nice Christmas tip. I started to cry. I went to IHOP. I gave a waitress a very nice tip for listening to me. I was in a terrible state after that. It was 6am. I had nowhere to go, and no one to talk too. I had 18 hrs of Christmas to survive. I figured it was better to do the smart thing then, instead of the dumb thing later. I checked into the emergency room. By noon I was in the psych. ward. It was a terrible place to be. I always have trouble following rules, and I have thing for authority. I was in trouble all the time. When I couldn't get in any more trouble, I would instigate others to do so. I would have never got to leave if it was up to the group therapist. After 4 days of hell, I got out. They have me on 4 different medication. I am starting to feel better, now.
What does all this have to do with the topic, you might ask?
I think most peoples depression is because their lives were fecal matter, absolutely nothing to do with random chemical brain in balances. There is a definatly a causal and effect going on. The same meds work. Because, a crappy life leads to an emballance. If those monsters that control everything, that call themselves normal, don't change their ways. Our country, and the rest of the world will just explode.

i think my problems are mostly from my brain chemistry, even right now nothing is really going wrong with my life besides the fact im failing out of grade 12( which is actually a huge problem but im just not thinking about it), but yet i still feel as bad as ever. like my brain is so messed that sometimes my mouth cant produce certain words, like a cd skipping or when you have to wait for your comp to load, i have to stop and concentrate so my brain can work properly so i can just speak.

but my brains current messed up chemisty is my fault, so hence my problems are all my fault... maybe someday they can replace the broken parts in me...

yah im just saying this to say that some ppl are really depressed and nothing can really change that without altering their brains chemical balance through drugs and/or cognative therapy, and trying that can do more damage then good...

remember that everything we have ever felt was because a lil chemical told us to feel that way, and when the chemicals slack off or get their stuff mixed up ppl dont act or feel normal

but then again what do i know...

It is the time and world we live in. We are all like mice running here and there getting nowhere.

The bigger problem is some of the mice have guns, and have cars they don't know how to drive.

I must agree dear Mike on that one.