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Conditions and Diseases > Lupus Forum > Systemic lupus erithematosus (SLE)
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Q: Systemic lupus erithematosus (SLE)
asked by: DoctorQuestion on December 19th, 2007
I am an African-American and Hispanic female with Lupus. I have 3 daughters that are African-American. What is the likelyhood of any of them ending up with Lupus, and what should I look out for? And I would also like to know what are my chances, if any, of being able to have more children.


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Dr. Nikola Gjuzelov , MD
replied on January 14th, 2008
Lupus Answer A3515
You wrote:"List of pre-existing conditions: Hair loss,insomnia,extreme weight changes,severe mood swings,bad PMS symptoms,constant headaches,swelling of face and joints, fatigue,dizziness,fainting

List of other diseases, conditions, or injuries and their treatment: Lupus (SLE), Rheumatoid Arthritis

Diagnosis that has been suggested: Lupus (SLE), Rheumatoid Arthritis

Current medical treatment: Plaquenil,Ibuprophen,Darvocet"


Systemic lupus erithematosus (SLE) is an autoimmune disorder wherein the immune system creates antibodies against its own body’s structures. Wrong immune response causes inflammation and can damage almost all the organs and tissues in the body.

The precise cause of SLE (as well as all other autoimmune diseases) is still unknown but there are certain data that suggest a certain genetic background of all autoimmune disorders. But presence of bad genes is not enough to develop SLE. It is also believed that some environmental factors (infections, ultra-violet irradiation, some drugs) can provoke or contribute to the development of SLE.

The genes responsible for SLE can be inherited from the parents or created (via mutation) during the spermatozoid production (spermatogenesis), egg-cell production (ovogenesis) and early stages of embryonic development. Nonetheless, you can get pregnant even if you are suffering from SLE.





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