I'm not resistant, but, have you tried all possible drugs? If so, have you tried the 'electroshock therapy' ? That could work...

I have tried ECT and lost several good and bad memories in that process. I have gone as far as having the VNS implant, very expensive. I don't know if in the long haul that will make an improvement. Not to be smart, but if I had not tried everything I wouldn't have done either of the last two options.