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Conditions and Diseases > Acne and Skin Disorders Forum > Isotretinoin Capsule Causes Elevated Liver Enzymes!
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Q: Isotretinoin Capsule Causes Elevated Liver Enzymes!
asked by: Herbie23 on December 7th, 2007
New User
I have an acne since I was 13 years old. I am 23 now. I tried different medicines and it didn't work. Topical here, and oral antibiotics there and still it was a problem. Then I tried isotretinoin capsule which was prescribed to me by my doctor. It's really amazing because of all the medications that i had used, this is the only drug that works. This is my fourth month of treatment. I am on 1 cap every other day. But my story is not yet done,lol.. I forgot to add that during the first 2 weeks of the first month, I was terrified because my acne flared up more than before. And then I realized that, it was a normal reaction of the body..It's like cleaning of the underlying skin wherein all the comedones are removed. then I saw the improvement on my skin during the 3rd week.All of the people who knows me noticed the improvement. I am regaining my confidence now which was lost over the past 10 years.

Right now, I am on Essentiale Forte 2x a day for 2 months plus 1 cap isotretinoin every other day. My doctor prescribed me an essentiale forte(liver supplement) because my SGPT and SGOT increased beyond the normal level. The normal SGPT is from 30-60 I guess. Mine rocketed to 107.

Whoever is a doctor in here, I would like to ask for help because I am so worried about my liver and kidneys (since it is a nephrotoxic or kidney damaging).

Will there be a problem with 107 SGPT? What management do you suggest me to do? I am planning to go to an internist because I think my dermatologist is not very intellectual with regards to internal medicine. I don't like to take a risk. We all know that once the kidneys are damaged, they are damaged forever and you will have to undergo dialysis. I don't want that to happen. Neither I would like to have Liver cirrhosis or whatever kidney disease.

Please help. your suggestions will be appreciated! Til then!
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