The high-dose, concentrated omega-3 fatty acids have effective mood stabilizing and antidepressant effects for many people with bipolar disorder. Omega-3 fatty acids are essential components of brain cell membranes, including those of neurotransmitter receptors.
Magnesium is interesting in bipolar disorder because of its chemical similarity to lithium (lithium being the drug most commonly used as a mood stabiliser) and
some studies were done where magnesium was added to other treatments to stop symptoms of mania or rapid cycling.