I imagine that it could. I have never been on depo, but antibiotics do render b/c pills ineffective.

10 times in 3 days? Holy hell I didn't know that was possible. Did the guy finish all the times??? Damn! I couldn't do that if I wanted to! Did you both take spanish fly or something???

Goodness, you make it sound impossible or something. Heck, i've done that lots of times. I get mad when my man can't go another time after we've already gone three or four.

No antibiotics dont effect depo as its already in your bloodstream.There are somethings which do react dont know which but I have antibiotics for 3 months on depo and no probs

jan x

Yes antibiotics can cancel out Depo. I was on Depo when I got pregnant with my youngest son. I was on antibiotics at the time I ovulated and according to my OB, the Depo was ineffective due to the medication and I was able to conceive. On the pamplet you get with the Depo Provera shot, if you pick it up from the pharmacy will tell you that Depo will become ineffective with antibiotics.

Antibiotics doesnt cancel out the Depo.. i recently had antibiotics and asked my doctor he said it didnt and i also was having unprotected sex and im fine! An yeah because its in your blood stream your fine!

Shoot........I'm sorry. The pharmaceutical company must be writing false information on their pamplets. Dang that sucks.

if you go on google... an type family planning in it brings up a leaflet and says on there that antibiotics doesnt affect it!

Once again it sucks that the pharmaceutical companies are publishing false information. However, they were correct in my case. You would think the companies that actually manufacture the drug would have more information than google, but I guess not. Good job researching Amy.