A couple of things come to mind here:
1) is she taking immunosuppressants for her lupus? If so, working in the hospital can certainly put her at risk for infections.
2) kidney pain: hmmm...It is my understanding and my experience that lupus nephritis rarely has pain involved. Has she talked to her rheumatologist about this...It could be something else. I know I had pain in the flank area and it was not my lupus nephritis flaring.
3) stress is horrible for lupus. Yes, it can keep it active...Which, in turn, makes the lupus worse. If she is stressed out because of work, then it probably is a problem.
4) pancreatitis? Is that what she had? That is very serious. I also know a lot of people that have digestive issues with their lupus, including myself, and it can cause cramping, nausea, vomiting, diarrhea, etc.
For the most part, discuss this with her doctor. They can make the best evaluation since they know her current and past history!
I wish you and your wife the best!
ladybrannon