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Conditions and Diseases > Hypoglycemia Forum > Diazoxide to inhibit insulin production ? Good results ?
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Q: Diazoxide to inhibit insulin production ? Good results ?
asked by: sleepy23 on October 10th, 2007
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Hi,

I have severe hypoglycemia. I am always low – I’ve tried a lot of things through diet first, no carb, low carb, high protein. It doesn’t help, I often pass out and need to be treated in the hospital emergency room. When I had my OGTT my fasting was 27, 1 hour 53, 2 hours 32 and 3 hours 14. The OGTT had to be stopped at 3 hours, but was meant to go for 4 hours.
Anyway, I saw an endocrinologist and have been put on a drug called diazoxide. I was told it’s meant to inhivit insulin production. I’ve been on it 3 days, it seems to be working. I’ve tested my fasting blood sugar twice and once 2 hours after a lettuce and tomato sandwich. The two fasting leves were 89 and 87 and 2 hours after my sandwich was 119. I feel a little bit better, not quite right just yet, guess it will take time, but I do seem to have a bit more energy and not as tired all the time so far. Kind of odd to have normal numbers. But just wondering has anyone tried this and did you see/have good results with it Question
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Stan
replied on October 14th, 2007
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I actually may be put on this soon. I'm being sent to an endicrinologist since, even though I've been able to stabilize my blood sugar on the diet, I cannot eat even the most minute amount of grains still. I will let you know what happens. As far as I've heard, you follow this for about a year, continuing to eat healthy during that time, ween off of it, and then you're fine as long as you keep eating well.
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Ron S
replied on November 8th, 2007
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I'm wondering if anybody actually knows someone who has tried this. I told my Endocrinologist about it (after learning about it here), and she never heard of it being used for hypo.
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Stan
replied on November 21st, 2007
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Apparently someone found my post offensive and has submitted it. I stand by what I said, if an endocrinologist does not know about diazoxide, they're a total waste of your money. This medicine exists specifically to block insulin, there's no way they wouldn't know about it unless they were very poorly educated. Does this mean I think she's stupid? No, it means I think she needs to go back to school before she harms someone by her lack of information. What do you call a medical student who graduates with a C- average? A doctor. Get it?
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sleepy23
replied on November 27th, 2007
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Stan, did you end up being put on diazoxide?
I'm having good results still - I seem to get bg's of 90 - 130 much of the time.
I think I'm eating quite healthy. Breakfast I go with wholemeal toast and diet jam with tea, lunch a salad sandwich (25g cho), salad with one piece of wholemeal bread (12.5g cho) or wrap (20g cho) and dinner just stir fry (no rice), chicken/fish with veggies or salad.

I drink tea, but have do coffee anymore and either snack on low carb foods (I make sure it's under 15g cho) or just celery.

The endo I've been seeing wants me to see a dietician though. So we'll see what comes of that.
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webfulfill
replied on June 5th, 2009
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Metabolic diet, rules of insulin production
I am learning about the metabolic diet. Basically it states that insulin is stimulated by any plant product, such as vegetables or fruits or even tea! Of course sugar and refined grains can cause the same effect.
They suggest that if one starts each meal with a protein food and then ends with a fruit, vegetable or tea, insulin is released more steadily. Also it is better to chew thoroughly (30 times). I have been trying this, but I am finding that I have to remove all sugars and grains of any kind. They say it takes getting used to, but I am still getting too much insulin!
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danab
replied on August 10th, 2009
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I know this is an old thread but if you are still around I would like to know If you are still on the med & how you are doing.
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