Anti-depressants are simply drugs, and there are many drugs designed to make a person feel good, unfortunately, most of those drugs are addictive. I would say all are, as people become dependent on the drug/medication for happiness.
Medication can not "choose" what you think about, it alters it. So does willpower. The same willpower enabling people to exercise to lose weight, or to even fast from all food for many days. Just as the brain is the largest "sex organ" (as they say), it is also the best organ to fight depression. Instead of using drugs to alter bad thoughts, start out with good thoughts! Thoughts of goals, futures, solutions, faith in God, etc. And, crying is ok, there are such things as tears of joy!
What matters after you die? Focus on that, and you will always have a reason to hope and be happy for a future. If nothing matters after death, then "happy" people are simply fooling themselves about what's coming. If you think suicide is an option, I recommend you start off with a 40 day water fast. Then, if you still wish to pass this life up, make it longer! No other way can a person express their anguish, and sometimes it is just being able to express yourself in that way that you will gain hope. And...you will never have such an appreciation for food : ) Maybe you'll start dreaming of new recipes, and become a famous chef : ] Have faith in God and follow Christ, God's promises are truth and you don't need to lie to feel better, because it is that hope that grows stronger every day as the hope of the world fades. And, dedication to God can help you overcome any destructive habits in your life directly causing depression/image/physical issues, such as drugs, smoking, binge-eating, etc.