Did you ever find out anything more conclusive in this case? I am very interested to know what the actual cause was if you found it.

So far he has been diagnosed with "Periodic Fever Syndrome" There are several kinds of this. He has to have DNA testing to find out which one. If he has one called Mediteranian Fever then he will have to take medication to protect his kindneys, but the think he has one that goes by PFAPA (long name) and he will grow out of it.

Kaseyd, thank you for your post. I've been searching high and low for information on frequent fevers in toddlers. My 19 month old daughter has frequent high fevers that at times spike up over 106 degrees. Every time we take her to doctor they tell us it's just viral. The times it has spiked over 106, we've gone to the ER and the basic tests they do always come back normal. My husband and I have an appointment with the pediatrician tomorrow to discuss bringing our daughter to a specialist.

Wow, this is just like my son. Since birth he has had fever and had ended up hospitalised due to it. He was over 40.6 and they found high imflamation markers in his blood but no infection. He continues to get these fevers and they have tested him for nearly everything. I get fed up with the Virus brush off that we often get.

would be interested in what information you get.

our son who is 8 months old keeps having these bounds of fever, like once every month and the doctors weren't able to figure out what have been wrong with him. Is it possible that this is due to some of illnesses. There were no other symptoms; the fevers just came without any warnings.

Thanks for your post. Seems we are not alone in this heart wrenching fever mystery. Our 19 months old son has been in the trenches with these fevers and we get the same feed back by our Doctors. We hope he does grow out of it soon, and we wish the same for your little ones. Keep you posted if we find anything new to share. Thanks

My son I 'm realizing has the same exact thing you are all talking about. Series of fevers we are now on our third in the last month in a half that gets up to 105. Wonder where this comes from ?

Hello everyone,
posted here a couple of weeks ago and wanted to share new information with you all. My son(20months) is still having these frequent fevers and we are in the middle of one now. our last episode 2 1/2 weeks ago, ended with yet another trip to the doctors. On this trip we learned about a clinic in Bethesda, Md with NIH(National Institute of Health). This Clinic is under Pediatric Rheumatology which includes Periodic Fever Syndrome. Our doctor is finishing up blood work to rule out a few things, and we are waiting on a test kit from the center. This is all new to us and we are still looking into it. here is the web site if you are interested...
niams.nih.gov

look under pediatric rheumatology

My daughter finally outgrew this at 4 yrs of age!! She had the same thing except her doctor just kept saying she had an overactive immune system and that everytime her body thought it was going to get sick she'd spike a fever. I couldn't even allow her around people with the common cold because it would reak havoc on her system.

has anyone gotten feedback from the test kit ? What does it entail?

So glad to hear that there are others out there. We've had five episodes since April of fevers that start at 103.7 and above, and we have to do the tylenol/motrin thing and sometimes have to add lukewarm baths to get fever down. When the 105 fever was there for 5 days, we went to the ER, where we found out the same old thing...VIRUS. So, at this point I"m tracking the fevers and will give the doc an update at her 2 year visit in Dec. I've googled it, and would prefer not to think of all the what-ifs!

Hello my son 15 1/2 months had a visit w/ an immunologist last week he actually had a fever on his appt. They gave 3 ml of Prednisolone and it was gone within hours and did not come back . Usually he would have the fever for another four-five days. I don't believe in this type of drug but it worked and its a clue that he may have one of the Periodic Fever Syndromes.

Did any of your children have slight rashes on their faces . He does and he also has now a rash raise and red dry spot on his shoulder.

Hi, My son is 20 months old and has had fevers on and off since july. We are now on the eleventh fever. The fevers usually start out to be viral and suddenly seem to turn bacterial after five days and the temp suddenly spikes. I have had to have him hospitalised once. He is usually put on antibiotics but after about 10 days after the last dose, he again develops a fever. I am at my wits end. We have done innumerable bllod works and urine cultures. I would be grateful for any insights.

Hello, Maybe someone here could help me. My daughter 2 years old always has a fever of 103 or higher. She has these fevers for soemtimes 3-4 days a week about every other week. Drs today ran some tests but i am extremly worried. She has had phenmonia four times since May. I rotate the medicine, give the baths. She hardly ever eats. Is there anything I can do? I am so worried I allready have lost a child I don't want to loose another. I am glad to know that I am not the other mother with this problem. Do these kids grow out of this? Anything will help thanks.

My little boy start with Unexplained Fevers since he has 8 months old. Now he is 3yrs and still has this rare fevers. Since the beginning he has an average of one fever every month or two. If somebody know something let me know.

my son now 2y 3 mths, was very sick with recurring fevers. Started with just vomiting at about 4 mths then fevers started a few weeks later. Dr's couldn't find why, kept saying to see what happened. Eventually found sores in his throat etc, treated him for bacterial infection, wow, fever gone after a week. 2 weeks later it was back again, this time he had a red ear so more antibiotics, wow, again fever gone after a week but back again 1 week later. this went on and on, there always seemed to be some infection somewhere, till he was 9 months old and it got so bad that we couldn't bring his temp down with 2 x meds and tepid bathing. He had convulsions and we rushed him to the ER. Turned out he had a urinary tract infection (UTI)which is not as common in boys as it is in girls and all the other infections where secondary to the UTI. The infection was so bad that the tester stick at the ER showed positive for all but 2 of the tests and yet this child never cried when he did a wee (no pain indicator), his urine did not smell strong or different (no smell indicator), and the colour of his urine did not appear cloudy, or of unusual colour. By the time he was treated (5 days in hospital on drips) his immune system was so run down that he had constant infections and we had to keep him isolated (at home) for 2 months so that he could build up his immune system again. Keeping him locked up at home for that time was hard on us all but it was worth it, we also gave him pro-biotics and iron supplements during this period. Except for grommets for glue ear he is now a very happy, boisterous terrible two year old. I hope you all find your answers as I know how hard it is but my experience has taught me 2 things, one is to always get a 2nd, 3rd or even a 4th opinion if your baby is just not right and the 2nd is to give your baby a chance to rebuild their immune system after they have been ill, especially when they are young. I don't mean the common cold stuff but if they get these constant fevers etc, give the isolation thing at home a go. Lots of water, love and rest. It is frustrating and can make finances a bit tough but it did work for us.

I have twin boys who get a fever that spike to around 104. They get these fevers every 3-5 weeks with no other symptoms, I spent the last year documenting this for my doctor but he says they are just fine. It is very unnerving. My one son had a febrile seizure a year ago because his temp spiked really high very rapidly. We are going to do another round of blood tests the next time they have the fevers and if they come back normal the doctor says we need to just let it go, that they are fine. I am worried about all the tylenol and motrin they are taking on a monthly basis. I am relieved however that there are other families out there going thru the same thing we are. Does anyone know when they typically grow out of these episodes??

I think we are all in the same boat...

My 2 yr old son has been admitted to hospital 12 times in the last 15 months with high fevers and usually related febrile convulsions.

On four occassions doctors diagnosed tonsillitis, three "upper respiratory tract infections", one pneumonia and ther rest have either been due to "viral" or "ear" infections.

Just out of hospital from our last admittance the temperature spiked for 5 days and only the strong IV antibiotics bought it down.

All blood tests come back normal and also throat swabs, urine tests etc.

We are awaiting a referral to a immunologist and I have worked out that these episodes occur anytime between 2.5 - 12.5 weeks apart (average is 39 days).

We are also on the shortlist for him to have grommets in the hope that this can reduce the episodes linked to ear infections.

Whilst we are in hospital the nurses are amazed how quickly his temperature can rise and how little effect paracetamol and nurofen help to keep it down.

I have spent over a month of the past year in hospital looking after my son and it seems that our social life is disappearing as it comes on so quickly and suddenly that we have to cancel everything to dash to A&E....

I'd love to know if steroids can help him, what dose and what type and how often?

I wouldn't touch steroids unless they are absolutely necessary. My first son had steroids at age 5 and his personality changed dramatically during that period - very depressed and morose which is very hard to deal with in a child. If the immunologist sees no alternative then go ahead but have you tried what we did with our 2nd boy (see rpkent(above in december)) and keep your child home for an extended period. I mean seriously keep them at home - no shops, no parks, no visiting friends or family. It is really hard and 2 months seems like a year but it made a huge difference for us and getting grommets was the final icing on the cake, we actually paid for private surgery to get the grommets done quick and it was worth every cent. He has been well and happy and finally has caught up on the developmental stages that he had missed eg, speech development, weight gain etc.