I am fair-skinned 54-year-old female. I'm just finishing up a continuous 30-day treatment of Carac cream on my hands and forearms.
Like some who have posted, roughly around the second week I started noticing red areas that progressively got worse. I was so impressed with how many spots were showing with treatment to my arms and hands that I took it upon myself to treat the temple areas on my face - as a kind of self imposed experiemnt. My temples have several areas now that are red, peeling (and ocassionally bleed).
I go to the doctor tomorrow and will ask for additional RX's for my face. I was amazed at how many spots I had on my forearms and hands (over 50), so I KNOW my face must have precancerous lesions too, even though they may not be visible (like the ones I now see on my forearms and hands). I'm impressed with the product and thankful for it!
As far as side effects ... I have NOT had any swelling or redness, other than the specific spots. I have had mild headaches, mild stomach issues, and neck pain -- but I can't say for sure they were caused by the carac cream. True, the treated area isn't pretty to look at, there is a lot of dryness, and peeling, even some itching which I think may be associated with healing.
I am a very self-conscious person so I'm not looking forward to treating my face, but I know it is the right thing to do ...... if I have any doubts I only have to look at the numerous spots on my healing arms/hand/temples. It may not be a fun process, but it may well save my life.
If you and your doctor think you may have AK, try it for yourself; everyone reacts differently. Hang in there. Believe me, if I can handle it, I'll bet you can too.
Good luck, and take care.