I have been looking up info on the compliment c4. The rhuemy only mentioned c3 and c4, I am now wondering if she measured c1. I guess this can be realted to kidney functions. I have been having other symptoms that I did not mention to her as, I thought they might be from weight gain. About a month ago, I was having edema in my legs when I woke in the am- also my eyes have looked puffy. Felt just like I did with pre-eclampsia. I also had upper right quad pain with the pre-eclampsia so, it may all be related. It lasted a few weeks, then....
It just so happened that my family practice doctor put me on a low fat, low cholestrol diet -as my cholestrol is high and my bloodpressure was going up/borderline high. My pressure was usually 116/75 (give or take a few points) almost never over 120/80. Now it's been around 134/85. After changing to an almost vegetarian diet, the swelling in my legs stopped.
I guess I call rhuemy's the office on monday.
I hope you don't mind me posting here.

I have yet to be diagnosis - just something auto-immune. The possibilities mentioned were lupus, ra, and thyroid. I know it can take a while to differentiate and get a correct diagnosis and it is harder when bloodwork is negative.
Thanks for your patience,
karen