Does Tamoxifen Cause Liver Cancer Posted: 07-13-07 03:37am
Hi there. My sister in low has a early
stage breast cancer and is taking
tamoxifen pills. I was doing some research
on the net and found out that tamoxifen
can cause liver cancer. Is this true ?
What is the connection between tamoxifen
and liver cancer ? thanks
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MandMs
Extremely EHEALTHy
Joined: 26 Jan 2007 Posts: 1963 Location: Strumica, Macedonia
Thanks: 30
Thanked:10
Posted: 09-13-07 05:50am
Hi!
It is not known Tamoxifen to cause liver
cancer in humans. Sometimes it can cause
other liver toxicities in patients, which
can be severe or life threatening. Blood
tests are usually performed from time to
time to check liver function.
I'm sure your sister in low will find
Tamoxifen beneficial. There are clinical
evidences, about tamoxifen used as
adjuvant therapy for early stage breast
cancer, that showed reduced risk of
recurrence of the original cancer and also
reduced risk of developing new cancers in
the other breast.
Best wishes!
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lrn10
New User, Becoming EHEALTHy
Joined: 18 Jan 2008 Posts: 1
Tamoxifen Posted: 01-18-08 06:38am
My mother was taking Tamoxifen for 5 years
after having breast cancer. She was just
diagnosed with primary liver cancer. It
was not metastatic cancer. I believe the
tamoxifen caused her liver cancer. She
had no previous liver damage. She did
drink alchohol but not heavily. I would
be careful while on Tamoxifen and make
sure to have tests done to monitor how
this drug is affecting your body. Another
women I know who took Tamoxifen also for 5
years, had to have a hysterectomy due to
suspicious changes in her uterus. I think
there needs to be more research on this
drug.
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jennyr
New User, Becoming EHEALTHy
Joined: 06 Feb 2008 Posts: 1
Liver cancer and tamoxifen Posted: 02-06-08 03:13am
My mother took part in a tamoxifen trial
in the UK. She had had a very early stages
lump removed from one breast with an
excellent prognosis as it was such early
stages.
Anyway, she agreed to take part in a 5
year tamoxifen trial. In the following
year after the end of the trial she was
diagnosed with cancer. She had multiple
liver metastases. They did a liver biopsy
but were not able to make a diagnosis of
the primary source. She died within 3
months of diagnosis of this incredibly
aggressive cancer. Also, while she was on
tamoxifen she had to have a hysterectomy
(very common as it affects the lining of
the womb. Also had cataracts, I think this
is common on this drug too.
She was incredibly fit and health with no
cancer in her side of the family. Don't
risk it. My mother would have been better
off not taking tamoxifen. Even if the
breast cancer had come back, she would
have had a much better prognosis as it's
more treatable.
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