Not really. Even doing it once or twice a day is not really considered dangerous. Never force yourself though, you have to want to.
I can't remember where I read that but to some extend it makes sense that since we produce a few million spermatozoids per hour, it's good to release once in a while (a couple of times a week is frankly enough).
The real danger is related to temperature and position: not too tight, not overheated (having your laptop on your legs is not good for example), and of course no injury (be careful when doing sports).