Interestingly, the back part of the thighs respond VERY WELL to regular exercise. If you can target the back of your thigh by doing leg lifts 10-15 minutes a day, you will notice that they decrease in size rather quickly (2-3 weeks). But it takes dedication and work!
As far as the inner thighs, you can also target these muscles to get a thinning effect via yoga or pilates. But I'm not sure about the quadraceps muscles on the front part of the thigh. This is a group of 4 large muscles grouped together whose shape is determined when you're born. Isometric contractions can help lengthen any muscles, so this is why yoga and pilates are helpful.